Neuropeptides derived from pro-opiocortin: behavioral, physiological, and neurochemical effects.
نویسندگان
چکیده
منابع مشابه
Behavioral and neurochemical effects of prenatal halothane
Permanent neurobehavioral toxicological effects have been theorized to occur at the lowest doses of a toxic agent if exposure occurs during early development compared to exposure during adulthood. Data are reviewed showing the exposure to 10 ppm of halothane from conception to day 60 of life post-partum led to adult rats (>/= 135 days of age) which were hyperalgesic to electric footshock and wh...
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متن کاملCharacterization of pro-opiocortin-converting activity in purified secretory granules from rat pituitary neurointermediate lobe.
Lysates of secretory granules from rat pituitary neurointermediate lobes were incubated with [3H]arginine- or [3H]phenylalanine-labeled toad pro-opiocortin. The processed products formed were identified by immunoprecipitation with adrenocorticotropin (ACTH) and endorphin antisera and by migration behavior on acid/urea/polyacrylamide gels. Pro-opiocortin was cleaved by the proteolytic activity i...
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ژورنال
عنوان ژورنال: Physiological Reviews
سال: 1982
ISSN: 0031-9333,1522-1210
DOI: 10.1152/physrev.1982.62.3.976